At Mannheim’s Nationaltheater, where he was Erster Kapellmeister, Mr Percacciolo conducted Rossini's Il Barbiere di Siviglia and Mozart's Le Nozze di Figaro, Jerry Bock's Anatevka, Engelbert Humperdinck's Hänsel und Gretel, Peter Maxwell Davies' The lighthouse, Puccini's Le Villi and Verdi's Il Trovatore. With the Heidelberger Sinfoniker he conducted a concert with Melanie Diener and Thomas Hampson as soloists. Other recent engagements included Il Barbiere di Siviglia, in a production by Filippo Crivelli/Daniela Zedda, at Teatro Lirico in Cagliari, a symphonic concert at Teatro Petruzzelli in Bari and in Florence at Maggio Musicale Fiorentino.

He was invited by the Rundfunk Sinfonieorchester in Berlin, the Philharmonische Camerata of the Berliner Philharmoniker, Orchestra Sinfonica Siciliana, Orchestra Toscanini in Parma, Orchestra di Padova e del Veneto, the Orchestra of Teatro Comunale in Bologna. He also collaborates regularly with the Philharmonische Camerata of the Berliner Philharmoniker as a pianist.

In 2021, Salvatore Percacciolo opened the opera season of Teatro Massimo Bellini in Catania with Rossini's Il Barbiere di Siviglia. At the Vollgutlager in Berlin he conducted the world première of Birke Bertelsmeier's musical installation The world to come with the Rundfunk Sinfonieorchester Berlin, a production by Tilman Hecker.

In past seasons he conducted Lucia di Lammermoor at Teatro Lirico in Cagliari, in a production by Denis Krief, Don Giovanni at Teatro Massimo Bellini in Catania, Rossini's La Cenerentola at Teatro Greco in Lecce, Tosca and Madama Butterfly at the Puccini Festival in Torre del Lago, La Bohème at Opera Theatre of Tirana. For the opera season of Teatro Sperimentale in Spoleto he conducted Rossini's Il Barbiere di Siviglia directed by Paolo Rossi, Britten's The Rape of Lucretia, and Mozart's Don Giovanni, in a production by Henning Brockhaus.

As an opera conductor, he made his debut with A.S.L.I.C.O opera domani conducting Mozart's Magic Flute (revived at the Royal Opera House in Muscat, Oman) thereafter Mozart’s La finta semplice. He received the Carlo Maria Giulini Award from Scuola di Musica di Fiesole and was invited by Lorin Maazel as a conductor fellow at the Castleton Festival in Virginia, USA. Maazel himself selected him as his deputy for Mozart's Don Giovanni at the Festival he founded and entrusted him with the world première of Derrick Wang's opera Scalia/Ginsburg and with Ravel’s L’heure espagnole. He had previously been assistant conductor in several opera productions at the Bayerische Staatsoper in Munich and Berlin, where he now lives.

A champion of contemporary music, Salvatore Percacciolo conducted the world première of Dioniso in Sicilia and Persistenze di memoria by Giovanni Ferrauto, Figlia del fuoco by Marco Taralli, Giufà by Joe Schittino, Istoria di Sant'Agata by Giovanni Sollima. For NAXOS he recorded a CD with music by Baska, Hidas, Krek and Papandopulo for piccolo flute, with soloist Francesco Viola and the Orchestra of the Nationaltheater Mannheim. Recent releases also include the short opera I due usignoli by Nicola Campogrande, with the Orchestra of Teatro Comunale Bologna and with the choir I piccoli cantori from Torino (with Lattes Edizioni).

An experienced symphonic conductor, Mr. Percacciolo has collaborated with major soloists including Roberto Cominati, Francesco D'Orazio, James Galway, Giovanni Sollima, and Uto Ughi. He was also the conductor of the Orchestra Sinfonica Siciliana's Youth Orchestra, where he conducted De Falla's El Retablo de Maese Pedro with Figli d'Arte Cuticchio in Palermo.

Salvatore Percacciolo graduated from Conservatorio Arcangelo Corelli in Messina as a pianist, studied composition at the Conservatorio Alessandro Scarlatti in Palermo and obtained a Master's degree in conducting at the Conservatorio Umberto Giordano in Foggia. A student of Piero Bellugi in Florence, he then graduated in 2010 from the Scuola dell'Opera Italiana in Bologna with Bruno Bartoletti and Nicola Luisotti, before completing his studies with Jorma Panula in Finland and Lorin Maazel in the US.

Salvatore Percacciolo is represented by Felsner Artists in Germany, Austria and Switzerland.